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KrosFlo® KR2i TFF Systems

KrosFlo® KR2i TFF systems achieve an unparalleled combination of configurability and user-simplicity through modular, plug-and-play hardware. All components, either directly or indirectly, connect to the main pump, which then communicates with the KF Comm 2 software for control and monitoring

Modularity Made Easy with KrosFlo® KR2i TFF System

KrosFlo® KR2i TFF systems achieve an unparalleled combination of configurability and user-simplicity through modular, plug-and-play hardware. All components, either directly or indirectly, connect to the main pump, which then communicates with the KF Comm 2 software for control and monitoring

Walk-away automation for your lab

The days of manually adjusting screw clamps are over. A Repligen-exclusive technology, the Automatic Back Pressure (ABV) Valve adds transmembrane pressure (TMP) control to every TFF process, reducing operator hands-on-time, data logging and continuous monitoring while improving process reproducibility.

  • Automatically adjust tubing pinch distance according to user-defined set-points
  • Maintain uniform TMP throughout process run, decreasing membrane fouling
  • Use with compatible tubing sizes 13, 14, 16, 25, HP15, 17, HP24, 18, HP35, 36, and HP36

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Standard and Configurable ProConnex® Flow Paths

ProConnex® Flow Paths are customized, configurable and complete assemblies for tangential flow filtration. Designed for use with hollow fiber and/or flat sheet TFF systems, the assemblies are sterile, fit for upstream or downstream processing and manufactured in compliance with ISO guidelines in an ISO 7 clean room.

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Effortless scaling with a single standardized platform

Designed as a platform and not as standalone units, KrosFlo KR2i, KMPi, and FS lab scale TFF systems share the same components, software and controls across the entire family, allowing you to confidently standardize your process. Common process change challenges during scale-up are removed.

 

System features at a glance

The fully integrated KrosFlo KR2i TFF System features a digital peristaltic pump, graphical LCD display, digital pressure monitor, KR2i Pump head, automatic backpressure valve, filter module stand, and KF Comm real-time data collection software.

Highly configurable and versatile, the KrosFlo KR2i utilizes a number user-defined set-points to run complex application processes with numerous built-in safety alarms and stops. The system can run up to two stackable pump heads for higher flow rates.

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