A must-read for all bioprocessing scientists: Eppendorf created four ebooks to explain the world of bioprocess applications, process and scale-up optimization, and digitalization.

 Addressing Bioprocessing Scale-Up Challenges

Traditional MAB therapies and newer biotherapeutics require different approaches for commercial production.

Cell and gene therapies present challenges and decisions for drug companies looking to manufacture them. However, differences in manufacturing cycles for emerging therapies compared with those of traditional MABs call for different strategies.

 Bioprocessing: Solutions for Vaccine Development

Vaccination has remained one of the most effective methods in the fight against viral diseases such as influenza. Pressured by COVID-19, an unprecedented surge in demand for efficient vaccine technology has engulfed the industry.

Biotherapeutics production involves cell line development, process development, and effective scaling. The key drivers of vaccine development are cost and yield.

 Increasing the Reproducibility of Cell Culture Bioprocesses

The inability to reproduce results from a successful bioprocessing run is not only frustrating to manufacturers, but it can also contribute to overall inefficiencies and increase the costs of drug development. Researchers waste precious time when reagents don't perform as expected—and this is one of the variables that likely contribute to irreproducibility.

 Upstream Bioprocessing: Improving efficiency through digital tools

Digitalization holds great promise for increasing efficiency, quality, and reproducibility in bioprocessing. Consider automation, process optimization through modeling and statistical methods, digital solutions for equipment maintenance, and cloud-based data handling.

With this ebook, we would like to explore how bioprocessing is becoming more digitalized.