Optimizing Cell and Gene Therapy Workflow

Cell and gene therapies (CGT) are emerging fields of transformative medicine where diseases are treated by restoring or reconditioning cells or genes. Although applications of CGT in medicine remain in their infancy, research and development of novel CGT are rapidly expanding. With an aim to develop treatments that may prevent, treat and cure genetic and acquired diseases, cell and gene therapies comprise overlapping fields of biomedical applications where cell cultivation is a fundamental technique. A major challenge is that cell culture processes must be scalable and standardized to produce large numbers of cells with consistently high quality.

Key Highlights

• Cell and Gene Therapy—A Perspective
• Cellular Therapy (CT) and Regenerative Medicine—Stem Cells
• Stem Cell Bioprocessing—Stirred-Tank Bioreactors
• Scalable Expansion of Human Pluripotent Stem Cells
• Interview: Stem Cell Cultivation in Bioreactors: Increasing hiPSC Yield
• Scalable Expansion of Human Bone Marrow-Derived Mesenchymal Stem Cells