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Automation of High - Throughput Flow Cytometry with the ZE5 Cell Analyzer
Integration of flow cytometers into automated workcells increases throughput, enables 24/7 operation, and provides consistent results. With hardware designed specifically to manage high-throughput sample handling and analysis, the ZE5 Cell Analyzer is robust and automation friendly.
What Can Be Accomplished through Automated High-Throughput Flow Cytometry
Historically, limited color detection, large sample volumes, and manual loading were the reality for flow cytometers. Modern flow cytometers have dramatically increased sampling capacity while decreasing the amount of sample needed for analysis. Today’s high-parameter cytometers detect dozens of colors/markers simultaneously, which saves precious samples and speeds up processing time. Now an entire plate of 384 samples can be analyzed in less than 60 minutes.
Features and Applications of the ZE5 Cell Analyzer
The ZE5 Cell Analyzer was built for high-throughput analysis with a focus on speed, flexibility, high-parameter analysis, and automation. The integrated sample loader is able to accommodate tube racks, 96-well plates, or 384-well plates. Screening is fast, with the ability to analyze up to 100,000 events per second. In high-throughput mode, a 96-well plate can be analyzed in less than 15 minutes and a 384-well plate in less than 60 minutes.
The ZE5 Cell Analyzer integrated into the Biosero Automated Plate Handling System.
Range of Applications for High-Throughput Flow Cytometry
- Antibody screening
- Immunophenotyping and immunoassays
- Phenotypic drug discovery
- Functional assays
- Target screening
- Receptor binding assays
- Protein-protein interactions
- Toxicity assays
- Hybridoma screening
Considerations for Automating Flow Cytometry
When deciding which steps in a process to automate, identify the steps of the workflow that are slowing time to results, such as
- Staff/Training
- Equipment
- Space
- Costs
Three Ways to High-Throughput Flow Cytometry
- Optimize High-Throughput Workflow and Data Analysis
- Continued Support and Maintenance
- Automation and Integration Products from Our Partners
